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>Home > Process Principles > Pelletizing > Pelletizing by Layering

   Pelletizing by Layering

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Fluid Bed

Drum coater

Vertical granulator

Pelletizer

Product handling

  WIP/CIP

 Technical processes

Company

Procell

  Control

 


Pellet build-up, layer by layer, around a given starting core.


  Powder Layering .
 

Suspension and solution layering.
 

Product advantages.
Round pellets, often with a separating layer for innovative and demanding forms of medicine with high amounts of active ingredient.
 
  Comparison.
Higher density than spray granulates and agglomerates.


Pellet diameter.

Between ca. 0.6
mm and 2.5mm.
 
 

Principle of the powder layering process 

 

 


Principle of the suspension and solution layering process

 

A starting grain or a pellet can be presented as the starting material. The pellet is built up to the required grain size by adding the layering substance one layer at a time.
Powder and binders, suspensions or solutions make suitable layering substances. The layers are densely applied due to the movement of the pellets in the rotor (-> Fluid Bed Pelletizing in the rotor).
Different layers of various types can be applied.
Thick layers can be applied to the starting grains, which, in the case of layers containing active ingredients, allow large amounts of active ingredient to be incorporated.

 

Product characteristics

Layered pellet
Layered pellet
 


Dust free
Round pellets
Good flow behaviour
Easy to dose
Compact structure
Low hygroscopicity
High bulk density
Dense, uniform surface
Narrow grain size distribution
Low abrasion
High active ingredient content possible
Optimum starting shape for subsequent coating
 

With suitable additives, pellets can be made into tablets or used to fill capsules. The round shape is ideal for uniform coating. Pellets are good for automatic dosing.
 

  Manufacturing options
For this process, Glatt offers Batch Fluid Bed Systems with batch sizes from 50
0g to 250kg/batch.
     

 

Process principles

Technical Processes

▶Fluid Bed Pelletizing









































































 

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