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Coating or encapsulation of particles by melting.
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Particle and pellet coating, micro coating, flavour encapsulation.
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Effective process. Fast coating. No evaporation of solvents
required.
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Product advantages. Protection against moisture. Delayed release of
active ingredients in the case of pharmaceutical drugs. Taste masking.
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Uniform and dense coatings. Low to high coating masses in comparison
with the particle to be coated.
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Coating thickness. Between ca. 25µm and
several hundred µm.
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Process Principles
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A very even application of the coating material is an important feature of
the coating process. Coatings must be dense and without mechanical damage and
cracks. Lipid/Hot melt coating is a very effective process for the application
of waxes and molten materials as protective films for manipulating the particle
properties.
Glatt offers Fluid Bed Coating (Top
Spray Coating, Bottom Spray Coating, Rotor Coating) as a technical solution for
coating different particles and tablets. For particles difficult to fluidize we
have developed the Glatt Spouted Bed
Technology. The coating fluid is sprayed onto solid materials, which are
presented to it. The introduction of process air causes the film coating to
solidify. Small droplets and a low viscosity ensure that the distribution is
uniform. The time and energy-intensive evaporation of solvents can be
dispensed with by the use of molten materials as coating liquids.
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Specific manipulation of the product characteristics of particles or tablets
such as:
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Shelf life
Hygroscopicity
Flowability
Surface structure
Solubility
Release of active ingredients
Taste
Smell
Behaviour when dissolving
Sensitivity to light
Visual attractiveness
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2-layer coating on micro pellets
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Manufacturing options
Glatt provides systems with different capacities:
Batch Fluid Bed Systems
with batch sizes - from 2g to 1500kg/batch (Top Spray Coating) - from 50g to 700kg/batch (Bottom Spray
Coating) - from 500g to 250kg/batch (Rotor Coating) Continuous Fluid Bed Systems with
throughputs from 20kg to 5t/h Spouted Bed Systems with throughputs
from 200g to 3t/h. |
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