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Powder particles. Immobilization of liquids.
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Modern process.
Build-up of agglomerates/granulates from
powder
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Comparison.
Agglomerates are looser and not as dense as spray
granulates and wet granulates.
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Product advantages.
Particles with porous structure.
Excellent
solubility.
Highly suitable for making into tablets.
Controllable grain
size distribution.
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Grain size distribution.
Grain sizes between 0.2mm and 2.5mm are usual.
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Process Principles
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Agglomeration in the fluid bed (-> Fluid
Bed Granulation) is a modern process for building up powder granulates. In
this process, powder is moistened in order to form liquid bridges between the
particles. The spray liquid can either be water or an organic solvent, a powder
dissolved in water or another binder. The moistened granulates are dried and
cooled as required.
Due to the relatively low mechanical forces in the fluid
bed, the agglomerates/granulates are loose, have a low bulk density and are
outstandingly soluble in water.
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Product characteristics |
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Dust free
Good flow behaviour
Easy to dose
Good dispersibility
Excellent solubility
Highly suitable for making into tablets
Low bulk density
Controllable grain size distribution
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Built-up agglomerate |
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Manufacturing options
For this process, Glatt offers systems with different capacities:
Batch Fluid Bed Systems with
batch sizes from 20g to 1.5t/batch.
Continuous Fluid Bed Systems with
throughputs from 20kg to 5t/h. |
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